Congenital Stationary Night Blindness
Congenital Stationary Night Blindness (CSNB) is a hereditary retinal disorder causing night blindness from an early age, particularly in Briards.
Detailed Description
CSNB is a non-progressive retinal disorder caused by a mutation in the RPE65 gene, resulting in impaired rod photoreceptor function. Affected dogs are unable to see in low-light conditions but typically have normal vision in daylight. The condition is present from birth and does not worsen over time.
Common Symptoms
- Night blindness
- Bumping into objects in low light
- Normal vision in daylight
Management Options
- Environmental adaptation (avoiding dark environments)
Frequently Asked Questions
Can CSNB be cured?
No, but affected dogs adapt well; gene therapy is experimental.
How is CSNB inherited?
It is inherited in an autosomal recessive manner; both parents must be carriers.
Is day vision affected?
No, only night vision is impaired.
Condition Details
📅
Typical Age of Onset
Congenital (present at birth; signs by 8–12 weeks)
📋
Testing Available
Yes
🔍
Diagnosing Methods
Genetic testing; Electroretinography (ERG); Clinical history and owner observation
🛡️
Preventative Measures
Genetic testing of breeding stock; Avoid breeding carriers or affected dogs
🔗
Related Conditions
Progressive Retinal Atrophy, Other forms of congenital blindness