Von Willebrand Disease Type II
A hereditary bleeding disorder caused by deficiency or dysfunction of von Willebrand factor, leading to abnormal clotting.
Detailed Description
Von Willebrand Disease Type II is an autosomal recessive disorder resulting in abnormal platelet function and increased bleeding tendency. It is more severe than type I and can cause life-threatening bleeding episodes after injury or surgery.
Common Symptoms
- Prolonged bleeding after injury or surgery
- Nosebleeds
- Gum bleeding
Management Options
- Desmopressin (DDAVP) for mild cases
- Blood transfusions for severe bleeding
Frequently Asked Questions
Is von Willebrand Disease inherited?
Yes, it is inherited in an autosomal recessive manner.
Can von Willebrand Disease be detected before symptoms?
Yes, DNA testing can identify carriers and affected dogs before clinical signs appear.
Condition Details
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Typical Age of Onset
Any age; often detected after surgery or trauma
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Testing Available
Yes
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Diagnosing Methods
DNA testing; Buccal mucosal bleeding time; vWF antigen assay
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Preventative Measures
DNA testing before breeding; Avoid affected/carrier matings
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Related Conditions
Hemophilia A, Thrombocytopenia