Von Willebrand Disease Type I
Von Willebrand Disease (vWD) Type I is an inherited bleeding disorder caused by a deficiency or dysfunction of von Willebrand factor, a protein essential for normal blood clotting.
Detailed Description
vWD Type I is the mildest form of this hereditary bleeding disorder, resulting in prolonged bleeding times. Severity varies, but most affected dogs are asymptomatic or have mild symptoms. It is most often detected during surgery or after trauma.
Common Symptoms
- Prolonged bleeding after injury or surgery
- Nosebleeds
- Bleeding gums
- Hematuria
Management Options
- Desmopressin (DDAVP) for mild cases
- Blood or plasma transfusions for severe bleeding
- Avoidance of trauma and certain medications
Frequently Asked Questions
Should all dogs be tested for vWD?
Yes, especially before breeding or surgery.
Can affected dogs be safely spayed or neutered?
Yes, with appropriate precautions and preoperative planning.
Is vWD curable?
No, but it can be managed.
Are all dogs with the gene affected?
No, many are asymptomatic carriers.
Can vWD develop later in life?
No, it is congenital.
Condition Details
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Typical Age of Onset
Any age; often detected during surgery or trauma
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Testing Available
Yes
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Diagnosing Methods
DNA testing; vWF antigen measurement; Buccal mucosal bleeding time
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Preventative Measures
Genetic testing before breeding; Pre-surgical screening
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Related Conditions
Hemophilia A, Platelet function disorders