Transitional Cell Carcinoma
Transitional cell carcinoma (TCC) is a malignant tumor of the urinary bladder, with Scottish Terriers having a markedly increased risk.
Detailed Description
TCC is an aggressive cancer arising from the bladder lining. The cause is multifactorial, with genetic predisposition and possible environmental triggers such as lawn chemicals. It often presents with urinary symptoms and can be fatal.
Common Symptoms
- Blood in urine (hematuria)
- Straining to urinate (stranguria)
- Frequent urination (pollakiuria)
- Urinary obstruction (advanced cases)
Management Options
- Nonsteroidal anti-inflammatory drugs (NSAIDs, e.g., piroxicam)
- Chemotherapy (mitoxantrone, vinblastine)
- Surgery (rarely curative)
- Radiation therapy (select cases)
Frequently Asked Questions
Why are Scottish Terriers prone to bladder cancer?
Genetic predisposition and possible environmental factors.
Can TCC be cured?
Rarely; most cases are managed, not cured.
What are early signs to watch for?
Blood in urine, straining, frequent urination.
Is there a screening test?
Yes, the BRAF mutation urine test is available.
Should I avoid lawn chemicals?
Yes, as a precaution.
Condition Details
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Typical Age of Onset
9–11 years
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Testing Available
Yes
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Diagnosing Methods
Abdominal ultrasound; Cystoscopy and biopsy; Urine BRAF mutation test; Urine cytology
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Preventative Measures
Minimize exposure to lawn chemicals and pesticides; Early screening in high-risk dogs
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Related Conditions
Urinary tract infection, Bladder stones