Thrombopathia
Thrombopathia is a hereditary platelet dysfunction causing abnormal bleeding, with a breed-specific form documented in Basset Hounds.
Detailed Description
Thrombopathia is an autosomal recessive disorder where platelets fail to function properly, leading to excessive bleeding after injury or surgery. The defect is due to a mutation affecting platelet aggregation, and while clinical disease is rare, carrier rates can be significant.
Common Symptoms
- Prolonged bleeding
- Nosebleeds
- Gum bleeding
- Excessive bruising
Management Options
- Supportive care during bleeding episodes
- Blood transfusions if severe
- Avoidance of trauma
Frequently Asked Questions
Is there a cure?
No cure, but the condition can be managed.
Can affected dogs be bred?
No, affected and carrier dogs should not be bred.
How is it diagnosed?
Genetic testing and platelet function tests.
Is it common?
Carrier rate is significant, but clinical disease is rare.
What precautions should owners take?
Avoid trauma and inform veterinarians before procedures.
Condition Details
📅
Typical Age of Onset
Puppyhood
📋
Testing Available
Yes
🔍
Diagnosing Methods
Buccal mucosal bleeding time; Platelet aggregation studies; Genetic testing
🛡️
Preventative Measures
Genetic screening before breeding
🔗
Related Conditions
Von Willebrand disease, Other coagulopathies