Renal Cortical Hypoplasia
Renal cortical hypoplasia is a hereditary kidney disorder leading to early-onset chronic kidney disease and renal failure.
Detailed Description
This condition involves abnormal development of the renal cortex, resulting in a reduced number of functioning nephrons. It is progressive and leads to chronic renal insufficiency, often manifesting in young dogs. The disease is suspected to be inherited and is more common in certain breeds, including the Bedlington Terrier.
Common Symptoms
- Polyuria
- Polydipsia
- Poor growth
- Weight loss
- Vomiting
- Lethargy
Management Options
- Supportive care (fluid therapy, renal diet, phosphate binders)
- Management of complications (hypertension, anemia)
Frequently Asked Questions
Can this condition be cured?
No, only supportive care is possible.
Is there a genetic test?
Not currently; diagnosis is by exclusion and biopsy.
How early can it be detected?
Signs may appear as early as 6 months.
Should siblings of affected dogs be bred?
No, due to suspected hereditary nature.
Condition Details
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Typical Age of Onset
6 months to 2 years
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Testing Available
No
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Diagnosing Methods
Bloodwork (BUN, creatinine, SDMA); Urinalysis; Renal ultrasound; Renal biopsy
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Preventative Measures
Avoid breeding affected dogs and close relatives
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Related Conditions
Acquired chronic kidney disease, Other congenital renal dysplasias