Pug Dog Encephalitis
Pug Dog Encephalitis (PDE), also known as necrotizing meningoencephalitis, is a breed-specific, fatal inflammatory brain disease almost exclusive to Pugs.
Detailed Description
PDE is characterized by severe inflammation and necrosis of brain tissue, leading to seizures, behavioral changes, and rapid neurological decline. The etiology is unclear but likely involves autoimmune and genetic factors. The disease is progressive and fatal, with most affected dogs dying or being euthanized within weeks to months of onset.
Common Symptoms
- Seizures
- Circling
- Blindness
- Behavioral changes
- Ataxia
Management Options
- Supportive care
- Anticonvulsants
- Immunosuppressive drugs
Frequently Asked Questions
Is PDE contagious?
No, it is not infectious.
Can PDE be cured?
No; treatment is palliative.
Is there a genetic test for PDE?
Risk assessment tests are available but not definitive.
What is the life expectancy after diagnosis?
Usually weeks to months.
Can PDE be prevented?
Only by avoiding breeding carriers.
Condition Details
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Typical Age of Onset
6 months to 3 years
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Testing Available
Yes
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Diagnosing Methods
MRI; CSF analysis; Exclusion of other causes; Definitive diagnosis post-mortem
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Preventative Measures
Genetic screening of breeding stock; Avoid breeding affected lines
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Related Conditions
Idiopathic epilepsy, Infectious encephalitis, Brain tumors