DogMatchUp
Health Condition

Lundehund Syndrome

Lundehund Syndrome is a hereditary gastrointestinal disorder causing chronic protein loss through the intestines, leading to malnutrition and immune dysfunction.

Detailed Description

Lundehund Syndrome is a complex, multifactorial disease involving abnormal dilation of intestinal lymphatic vessels (lymphangiectasia), chronic inflammation, and sometimes gastric atrophy. It results in excessive loss of proteins into the gut, causing hypoproteinemia, edema, weight loss, diarrhea, and increased susceptibility to infections. The condition is believed to have a strong genetic component, possibly polygenic, with environmental factors influencing onset and severity.

Common Symptoms

  • Chronic or intermittent diarrhea
  • Vomiting
  • Weight loss
  • Lethargy
  • Edema (limbs or abdomen)
  • Poor coat condition
  • Loss of appetite

Management Options

  • Dietary management with low-fat, highly digestible diets
  • Immunosuppressive drugs
  • Vitamin supplementation
  • Diuretics for edema
  • Antibiotics for secondary infections

Frequently Asked Questions

Is Lundehund Syndrome curable?

No, it is a lifelong condition, but symptoms can often be managed with diet and medication.

Can Lundehund Syndrome be prevented with genetic testing?

No direct genetic test exists; careful breeding and early screening are recommended.

What is the first sign of Lundehund Syndrome?

Chronic or intermittent diarrhea and unexplained weight loss are often the earliest signs.

How common is this syndrome in other breeds?

It is extremely rare outside the Norwegian Lundehund.

What diet is recommended for affected dogs?

Low-fat, highly digestible diets, often with hydrolyzed or novel proteins.

Condition Details

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Typical Age of Onset

2–7 years, but can occur as early as 6 months or as late as 10 years

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Testing Available

Yes

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Diagnosing Methods

Blood tests for hypoalbuminemia and hypoglobulinemia; Fecal alpha-1 protease inhibitor test; Abdominal ultrasound; Intestinal biopsies

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Preventative Measures

Early detection through routine screening; Prompt dietary management

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Related Conditions

Inflammatory bowel disease, Exocrine pancreatic insufficiency, Other causes of protein-losing enteropathy