Lethal Acrodermatitis
A rare but fatal inherited skin and immune disorder characterized by poor growth, skin lesions, and immunodeficiency.
Detailed Description
Lethal acrodermatitis is caused by a mutation affecting zinc metabolism, leading to severe skin lesions, poor growth, and recurrent infections. Affected puppies rarely survive beyond two years, even with supportive care.
Common Symptoms
- Poor growth
- Crusting and ulceration of skin
- Diarrhea
- Recurrent infections
Management Options
- Supportive care
- Zinc supplementation
- Antibiotics
Frequently Asked Questions
Is there a cure for LAD?
No, only supportive care is possible.
Can carriers be identified?
Yes, with a DNA test.
Should all dogs be tested?
All breeding dogs should be tested.
Is LAD the same as zinc deficiency?
No, LAD is a genetic disorder.
Can affected puppies survive to adulthood?
Rarely; most die young.
Condition Details
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Typical Age of Onset
By 6-8 weeks of age
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Testing Available
Yes
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Diagnosing Methods
Clinical signs; Skin biopsy; Genetic testing
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Preventative Measures
DNA testing of breeding stock; Avoid breeding carriers
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Related Conditions
Zinc-responsive dermatosis