Inflammatory Myopathy (Polymyositis)
A rare but breed-associated immune-mediated muscle disease causing progressive muscle weakness and atrophy.
Detailed Description
Polymyositis is an autoimmune disorder where the immune system attacks skeletal muscle fibers, leading to inflammation, weakness, and muscle wasting. Dutch Shepherds have been reported to have a breed predisposition, with several familial cases documented.
Common Symptoms
- Progressive generalized muscle weakness
- Exercise intolerance
- Muscle atrophy
- Difficulty swallowing (dysphagia)
- Stiff gait
Management Options
- Immunosuppressive therapy (corticosteroids, azathioprine)
- Supportive care such as physical therapy and nutritional support
Frequently Asked Questions
Is polymyositis common in Dutch Shepherds?
It is rare but has a documented breed predisposition.
What are the early signs?
Weakness, muscle wasting, and exercise intolerance.
How is it diagnosed?
Muscle biopsy and elevated CK levels.
Can affected dogs recover?
Many improve with immunosuppressive therapy, but relapses can occur.
Is there a genetic test?
No; diagnosis is based on clinical and laboratory findings.
Condition Details
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Typical Age of Onset
1-6 years
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Testing Available
No
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Diagnosing Methods
Clinical examination; Elevated creatine kinase (CK) levels; Electromyography (EMG); Muscle biopsy
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Preventative Measures
Do not breed affected or carrier dogs
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Related Conditions
Muscular dystrophy, Myasthenia gravis