Hypoadrenocorticism
Addison’s disease is an endocrine disorder caused by insufficient production of adrenal hormones, leading to potentially life-threatening electrolyte imbalances.
Detailed Description
Addison’s disease is thought to be immune-mediated and hereditary in some breeds. It results in deficient production of glucocorticoids and mineralocorticoids, causing weakness, vomiting, diarrhea, and collapse. The disease can be acute (Addisonian crisis) or chronic with vague symptoms.
Common Symptoms
- Lethargy
- Vomiting
- Diarrhea
- Weakness
- Collapse
- Dehydration
- Bradycardia
Management Options
- Lifelong hormone replacement (prednisolone, fludrocortisone or DOCP)
- Emergency stabilization for Addisonian crisis
Frequently Asked Questions
Is Addison’s disease fatal?
Not if diagnosed and treated promptly.
Can Addison’s be cured?
No, but it is manageable with medication.
What triggers an Addisonian crisis?
Stress, illness, or missed medication.
Are there genetic tests for Addison’s?
No direct test, but family history is important.
How often are medications given?
Daily or monthly, depending on the drug.
Condition Details
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Typical Age of Onset
2–6 years
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Testing Available
Yes
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Diagnosing Methods
ACTH stimulation test; Electrolyte analysis (Na:K ratio)
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Preventative Measures
Screening of breeding stock; Early recognition of symptoms
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Related Conditions
Gastroenteritis, Renal failure