Greyhound Polyneuropathy
Greyhound polyneuropathy is a rare, inherited neurological disorder causing progressive weakness and muscle atrophy in young Greyhounds.
Detailed Description
This degenerative disease of peripheral nerves leads to muscle wasting, weakness, and gait abnormalities. It is caused by a mutation in the NDRG1 gene and is inherited in an autosomal recessive manner. The disease is progressive and debilitating.
Common Symptoms
- weakness
- ataxia
- muscle atrophy
- decreased reflexes
- difficulty rising
Management Options
- supportive care
Frequently Asked Questions
Is there a test for Greyhound polyneuropathy?
Yes, a DNA test is available for the NDRG1 mutation.
Can affected dogs live a normal life?
No, the disease is progressive and debilitating.
Condition Details
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Typical Age of Onset
Juvenile (3-9 months)
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Testing Available
Yes
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Diagnosing Methods
neurological exam; electromyography; nerve biopsy; genetic testing
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Preventative Measures
genetic testing of breeding stock
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Related Conditions
laryngeal paralysis, other polyneuropathies