Cushing’s Disease
Cushing’s disease (hyperadrenocorticism) is an endocrine disorder caused by excessive cortisol production, leading to a range of metabolic disturbances.
Detailed Description
Cushing’s disease is most commonly due to a pituitary tumor or, less frequently, an adrenal tumor. It leads to increased thirst, urination, appetite, and a pot-bellied appearance. The disease is chronic and requires lifelong management.
Common Symptoms
- Increased thirst and urination
- Increased appetite
- Pot-bellied appearance
- Hair loss
- Thin skin
Management Options
- Medical management (trilostane, mitotane)
- Surgical removal of adrenal tumors
Frequently Asked Questions
Is Cushing’s disease curable?
Not usually, but it can be managed long-term.
How is it diagnosed?
Through a combination of clinical signs and endocrine testing.
Is it painful?
Not directly, but complications can affect quality of life.
Can my dog live a normal life with Cushing’s?
Many dogs do well with treatment.
Is it inherited?
The exact inheritance is unknown, but breed predisposition suggests a genetic component.
Condition Details
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Typical Age of Onset
7–12 years
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Testing Available
Yes
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Diagnosing Methods
Clinical signs and history; Blood and urine tests; Endocrine function tests; Abdominal ultrasound
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Preventative Measures
No known prevention; early detection is key
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Related Conditions
Diabetes mellitus, Hypothyroidism