Curly Coat/Dry Eye Syndrome
Curly Coat/Dry Eye Syndrome is a rare but severe inherited disorder causing dry eye and abnormal skin and coat in affected dogs.
Detailed Description
This syndrome is caused by a mutation in the FAM83H gene, affecting skin and tear gland development. It leads to severe dry eye and skin problems from a young age, which can result in blindness and significant skin disease.
Common Symptoms
- Dry, flaky skin
- Curly, brittle coat
- Severe dry eye
- Corneal ulcers
Management Options
- Intensive eye lubrication
- Topical cyclosporine
- Skin care with moisturizers and medicated shampoos
Frequently Asked Questions
Can Curly Coat/Dry Eye Syndrome be cured?
No, only managed.
Is it common?
Now rare due to DNA testing.
Should affected dogs be bred?
No.
How is it diagnosed?
DNA test and clinical signs.
What are the first signs?
Dry, flaky skin and abnormal coat in puppies.
Condition Details
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Typical Age of Onset
Neonatal (first weeks of life)
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Testing Available
Yes
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Diagnosing Methods
DNA testing; Clinical signs; Schirmer tear test
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Preventative Measures
DNA testing of breeding stock
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Related Conditions
Primary keratoconjunctivitis sicca, Ichthyosis