Chronic Active Hepatitis
Chronic active hepatitis is a progressive liver disease often associated with copper accumulation and immune-mediated injury, leading to liver failure if untreated.
Detailed Description
This condition is characterized by ongoing liver inflammation, fibrosis, and eventual liver failure. Copper-associated hepatitis is particularly noted in some breeds, and early detection is important for management.
Common Symptoms
- Lethargy
- Poor appetite
- Vomiting
- Jaundice
- Ascites
Management Options
- Copper chelation (D-penicillamine)
- Low-copper diet
- Immunosuppressive drugs
Frequently Asked Questions
Is chronic hepatitis curable?
No, but it can be managed if caught early.
Should dogs have routine liver tests?
Yes, annual screening is recommended.
Can diet help?
Yes, low-copper diets are beneficial.
Is it inherited?
Copper-associated form is likely inherited.
What are the first signs?
Lethargy and poor appetite.
Condition Details
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Typical Age of Onset
4–7 years
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Testing Available
Yes
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Diagnosing Methods
Bloodwork (liver enzymes); Liver biopsy
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Preventative Measures
Screening breeding stock; Early liver enzyme monitoring
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Related Conditions
Infectious hepatitis, Other metabolic liver diseases