Cerebellar Abiotrophy
Cerebellar abiotrophy is a rare, inherited neurodegenerative disorder causing progressive loss of coordination due to cerebellar cell death.
Detailed Description
Cerebellar abiotrophy results from premature degeneration of Purkinje cells in the cerebellum, leading to ataxia, tremors, and loss of balance. The condition is progressive and ultimately debilitating.
Common Symptoms
- Ataxia (uncoordinated gait)
- Intention tremors
- Loss of balance
- Wide-based stance
Management Options
- Supportive care
Frequently Asked Questions
Is there a cure for cerebellar abiotrophy?
No, only supportive care is possible.
Can affected puppies live normal lives?
No, quality of life is severely impacted.
Is there a genetic test?
Not currently for most breeds.
How is it diagnosed?
By neurological exam and MRI.
Can it be prevented?
Only by avoiding breeding affected lines.
Condition Details
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Typical Age of Onset
Juvenile onset (6 weeks–6 months)
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Testing Available
No
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Diagnosing Methods
Neurological examination; MRI; Histopathology (post-mortem)
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Preventative Measures
Avoid breeding affected lines; Report cases to breed health registries
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Related Conditions
Cerebellar hypoplasia, Other inherited ataxias