Canine Inherited Demyelinative Neuropathy
A rare but breed-documented inherited neurological disorder causing progressive weakness and paralysis in young dogs.
Detailed Description
Canine Inherited Demyelinative Neuropathy (CIDN) is a severe, autosomal recessive demyelinating polyneuropathy. Affected puppies develop progressive hind limb weakness, ataxia, and eventual paralysis due to loss of myelin in peripheral nerves.
Common Symptoms
- Hind limb weakness
- Ataxia
- Loss of reflexes
- Progression to paralysis
Management Options
- Supportive care only
Frequently Asked Questions
Is there a cure for CIDN?
No, it is progressive and fatal.
Can carriers be identified?
Genetic testing may be available through research labs.
Should affected lines be bred?
No, both parents of affected puppies are carriers.
Condition Details
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Typical Age of Onset
2 to 4 months (puppies)
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Testing Available
Yes
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Diagnosing Methods
Neurological exam; Electromyography; Nerve conduction studies; Nerve biopsy
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Preventative Measures
Genetic testing and exclusion of carriers from breeding
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Related Conditions
Degenerative myelopathy, Spinal cord injury